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The clinical specialty of endocrinology focuses on the
endocrine organs, i.e. the organs whose primary function
is hormone secretion.
Hormones are chemicals that are manufactured in certain
organs of the body and travel through the bloodstream with
the purpose of maintaining and regulating the growth and
activity of other organs and the body as a whole. In fact,
there is not one aspect of human growth and development
that is not affected by hormones.
Endocrine Organs include the:
Adrenal glands: these two small glands are located on top
of each kidney. The adrenal glands consist of two parts each
of which secretes a different hormone. The adrenal cortex
secretes steroidal hormones which influence the metabolism
of carbohydrates, fats and proteins; maintain normal blood
pressure; and have an anti-inflammatory effect during times
of stress. They also secrete sex hormones necessary for
the growth of secondary sex characteristics in males and
females. The adrenal medulla secretes non-steroidal
hormones that play an important role in the body’s response
to stress. They increase heart rate, dilate the bronchioles,
raise glucose levels of the blood and raise blood pressure.
Pancreas: located in the upper left part of the abdomen,
the pancreas produces hormones (including insulin) which is
responsible for regulating the amount of glucose in the blood.
Pituitary Gland: a pea sized structure located at the base
of the brain. This “Master Gland” has an effect on nearly all
body functions.
Thyroid gland: located in the neck & attached to the trachea,
the thyroid regulates growth, controls body temp & metabolism.
It also regulates the amount of calcium in the blood.
Parathyroid glands: four round tissues on the back of the
thyroid gland. Together with the thyroid they help regulate
the amount of calcium in the blood.
Thymus gland: primarily responsible for the development
of the immune system.
Pineal gland: Pinecone shaped gland located in the
midbrain secretes a hormone, melatonin, that seems to
have a role in promoting sleep.
Ovaries: Produce the hormones Estrogen & Progesterone
which are responsible for the maturation of the egg, preparing
the uterus for implantation of a fertilized egg and the growth
and development of the placenta. Estrogen is also necessary
for the development of secondary female characteristics.
Testes: male sex glands produce testosterone, the
hormone responsible for the maturation of sperm and the
development of male secondary sex characteristics.
The skin, intestines, heart, and many other organs
have some endocrine functions as well.
With such a wide range of endocrine organs it should come
as no surprise that there are a wide range of endocrine
disorders and each can vary significantly in terms of severity.
Following is a brief list of endocrine disorders.
Adrenal disorders:
Adrenal insufficiency
Addison's disease
Congenital adrenal hyperplasia (adrenogenital syndrome)
Mineralocorticoid deficiency
Conn's syndrome
Cushing's syndrome
Pheochromocytoma
Adrenocortical carcinoma
Glucose homeostasis disorders:
Diabetes mellitus
Hypoglycemia
Idiopathic hypoglycemia
Insulinoma
Metabolic bone disease:
Osteoporosis
Osteitis deformans (Paget's disease of bone)
Rickets and osteomalacia
Pituitary gland disorders:
Diabetes insipidus
Hypopituitarism (or Panhypopituitarism)
Pituitary tumors
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